Heparin-Induced Thrombocytopenia (HIT) Review

Heparin-induced thrombocytopenia (HIT) is a dangerous complication of heparin exposure. In HIT, the body creates an autoantibody against the complex of platelet factor 4 bound to heparin. The anti-PF4 autoantibodies can activate platelets and cause life- and limb-threatening clots in arteries and veins. In HIT, platelets generally fall by more than 50% five to ten [… read more]

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Source: PulmCCM

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