CRACKCast E028 – Jaundice

This episode of CRACKCast covers Rosen’s Chapter 28, Jaundice. Show Notes – Link HERE 1) Describe heme metabolism Jaundice = elevated serum bilirubin Conjugated bilirubin = direct bilirubin Unconjugated bilirubin = indirect bilirubin (can cross blood brain barrier) – does not bind albumin unconjugated levels of bilirubin that is not bound to albumin is able to cross the blood-brain barrier and leads to adverse neurologic effects developmental abnormalities, encephalopathy, death is exacerbated by any …

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